The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 17, 2009
Filed:
Sep. 28, 2007
Charles Lemme, Tucson, AZ (US);
William Richards, Tucson, AZ (US);
David Bryant, Raleigh, NC (US);
Catherine Wolf, Eckbolsheim, FR;
Andrew Ghusson, Tucson, AZ (US);
Austin Ashby, Tucson, AZ (US);
Wayne Showalter, Tucson, AZ (US);
Anthony Hartman, Tucson, AZ (US);
Brian Kram, Tucson, AZ (US);
Charles Lemme, Tucson, AZ (US);
William Richards, Tucson, AZ (US);
David Bryant, Raleigh, NC (US);
Catherine Wolf, Eckbolsheim, FR;
Andrew Ghusson, Tucson, AZ (US);
Austin Ashby, Tucson, AZ (US);
Wayne Showalter, Tucson, AZ (US);
Anthony Hartman, Tucson, AZ (US);
Brian Kram, Tucson, AZ (US);
Ventana Medical Systems, Inc., Tucson, AZ (US);
Abstract
The present invention introduces a radically different way of accelerating biomolecule conjugates into tissue, and hence towards their targets for purposes of tissue staining. The invention provides for an order of magnitude improvement over the prior art diffusion process used to stain tissue. The invention comprises a method of tissue staining by applying an electric field to a tissue sample in the presence of an electrolyte and biomolecular conjugates of interest suspended in the electrolyte. Typical staining times are reduced to seconds as opposed to 30-120 minutes common in the prior art. The invention is also directed to devices for performing the method.