The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7615627 B1

PDF
Full Text
Expired
Date of Patent:
Nov. 10, 2009

Filed:

Jun. 19, 2007
Applicants:

Murali Krishna Addepalli, Maharashtra, IN;

Vidyadhar Eswar Chandra Gopavaram Reddy, Maharashtra, IN;

Inventors:
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C07H 21/02 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to the use of short nucleic acid molecules that modulate Aurora-B kinase (AurkB) expression. The invention includes compounds, compositions and methods useful for the modulation of expression and activity of genes involved in the AurkB pathway. In one embodiment, the present invention provides short nucleic acid molecules, such as siRNA, which can be used in treating, preventing, or inhibiting cancer, and any other proliferative disease, trait or condition, which respond to a reduction in AurkB expression in a cell or tissue. Such short nucleic acid molecules can be used alone or in combination with other treatments or therapies, including short nucleic acid molecules that modulate expression of EGFR.


Find Patent Forward Citations

Addepalli, Murali. (2009). Rna interference mediated inhibition of aurorakinase b and its combinations as anticancer therapy (U.S. Patent No. 7615627). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7615627

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