The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 10, 2009

Filed:

Apr. 08, 2004
Applicants:

Birgit Bollbuck, Weil am Rhein, DE;

Alastair Denholmmritain, Horsham, GB;

Jörg Eder, Rheinfelden, DE;

René Hersperger, Münchenstein, CH;

Philipp Janser, Basel, CH;

Lászlo Révész, Therwil, CH;

Achim Schlapbach, Lörrach, DE;

Rudolf Wálchi, Basel, CH;

Inventors:

Birgit Bollbuck, Weil am Rhein, DE;

Alastair DenholmMritain, Horsham, GB;

Jörg Eder, Rheinfelden, DE;

René Hersperger, Münchenstein, CH;

Philipp Janser, Basel, CH;

Lászlo Révész, Therwil, CH;

Achim Schlapbach, Lörrach, DE;

Rudolf Wálchi, Basel, CH;

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/42 (2006.01); C07D 403/04 (2006.01); A61K 31/506 (2006.01);
U.S. Cl.
CPC ...
Abstract

A compound of formula I or a pharmaceutically acceptable salt, ester or prodrug thereof wherein the variables have the meanings as defined in the specification. Further disclosed are a method of inhibiting IKK activity using a compound of formula I, a method of inhibiting production of TNF using a compound of formula I, a compound of formula I for use as a pharmaceutical, a pharmaceutical composition comprising a compound of formula I, and use of a compound of formula I in the manufacture of a medicament for use as an immunosuppressant or anti-inflammatory agent.


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