The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7615361 B1

PDF
Full Text
Expired
Date of Patent:
Nov. 10, 2009

Filed:

Mar. 06, 2007
Applicant:

James M. Mckim, Kalamazoo, MI (US);

Inventor:

James M. McKim, Kalamazoo, MI (US);

Assignee:

Ceetox, Inc., Kalamazoo, MI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/02 (2006.01); C12Q 1/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides methods of determining a level of toxicity of a given compound based on in vitro assays. The present invention provides particular methods of determining organ-specific toxicity and species-specific toxicity of a given compound based on in vitro assays. In addition, the present invention provides methods of determining a level of toxicity in normal tissue for an anti-tumor compound. The methods include providing at least one cell type and culturing the cell type in the presence of at least one concentration of the chemical compound, measuring at least one indicator of cell health at the at least one concentration of compound for the at least one cell type, and performing a concentration response analysis, from which a toxic concentration can be determined.


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McKim, James. (2009). Toxicity screening methods (U.S. Patent No. 7615361). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7615361

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