The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 10, 2009
Filed:
Jul. 06, 2009
Applicants:
Jie Lin, W. Roxbury, MA (US);
Murray Robinson, Boston, MA (US);
Bin Feng, N. Reading, MA (US);
Wenping Kathryn Sun, Cambridge, MA (US);
Inventors:
Jie Lin, W. Roxbury, MA (US);
Murray Robinson, Boston, MA (US);
Bin Feng, N. Reading, MA (US);
Wenping Kathryn Sun, Cambridge, MA (US);
Assignee:
AVEO Pharmaceuticals, Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C12P 19/34 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
A diagnostic method for predicting quantitatively whether a human tumor will be responsive or resistant (non-responsive) to treatment with the VEGF inhibitor, tivozanib (AV-951), is disclosed. The test is based on application of an algorithm to measurements of expression levels of the genes in a predictive gene set.