The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 10, 2009

Filed:

Oct. 17, 2005
Applicants:

Kenya Shitara, Fujisawa, JP;

Mikito Ito, Machida, JP;

Nobuo Hanai, Sagamihara, JP;

Yoko Kawada, Abiko, JP;

Kazuyasu Nakamura, Machida, JP;

Masabumi Shibuya, Kawaguchi, JP;

Inventors:

Kenya Shitara, Fujisawa, JP;

Mikito Ito, Machida, JP;

Nobuo Hanai, Sagamihara, JP;

Yoko Kawada, Abiko, JP;

Kazuyasu Nakamura, Machida, JP;

Masabumi Shibuya, Kawaguchi, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/00 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides an antibody or peptide which immunologically reacts with human VEGF receptor Flt-1 and cells in which human VEGF receptor Flt-1 is expressed on the cell surface and an antibody or peptide which inhibits binding of human VEGF to human VEGF receptor Flt-1. It also provides a means for the diagnosis or treatment of diseases in which their morbid states progress by abnormal angiogenesis, such as proliferation or metastasis of solid tumors, arthritis in rheumatoid arthritis, diabetic retinopathy, retinopathy of prematurity, psoriasis, and the like.


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