The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 03, 2009
Filed:
Aug. 26, 2005
Junji Miyata, Chuo-ku, JP;
Masaki Yokota, Chuo-ku, JP;
Ryo Naito, Chuo-ku, JP;
Akio Kamikawa, Chuo-ku, JP;
Masakatsu Kawakami, Chuo-ku, JP;
Kazuyuki Hattori, Chuo-ku, JP;
Junji Miyata, Chuo-ku, JP;
Masaki Yokota, Chuo-ku, JP;
Ryo Naito, Chuo-ku, JP;
Akio Kamikawa, Chuo-ku, JP;
Masakatsu Kawakami, Chuo-ku, JP;
Kazuyuki Hattori, Chuo-ku, JP;
Astellas Pharma Inc., Tokyo, JP;
Abstract
The present invention relates to a 2-phenylthiophene derivative or a salt thereof, wherein the thiophene ring is substituted with a carboxyl group or the like and the benzene ring has an electron-withdrawing group such as a cyano group and an electron-donating group such as a substituted alkoxy group at the same time. Since the compound of the invention has good xanthine oxidase-inhibitory action and uric acid-lowering action and does not have a structure derived from nucleic acid, the compound has advantages of high safety and excellent effects as compared with conventional compounds and is useful as a therapeutic or preventive agent for hyperuricemia, gout, inflammatory bowel diseases, diabetic kidney diseases, diabetic retinopathy, or the like.