The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 03, 2009
Filed:
Apr. 04, 2008
Karl Schoenafinger, Alzenau, DE;
Stefanie Keil, Frankfurt am Main, DE;
Matthias Urmann, Frankfurt am Main, DE;
Hans Matter, Frankfurt am Main, DE;
Maike Glien, Frankfurt am Main, DE;
Wolfgang Wendler, Frankfurt am Main, DE;
Karl Schoenafinger, Alzenau, DE;
Stefanie Keil, Frankfurt am Main, DE;
Matthias Urmann, Frankfurt am Main, DE;
Hans Matter, Frankfurt am Main, DE;
Maike Glien, Frankfurt am Main, DE;
Wolfgang Wendler, Frankfurt am Main, DE;
Sanofi-Aventis, Paris, FR;
Abstract
The present invention comprises bicyclic aryl-sulfonic acid [1,3,4]-thiadiazol-2-yl-amides, their functional derivatives thereof as well as their physiologically acceptable salts and pharmaceutical compositions thereof that exhibit peroxisome proliferator activated receptor (PPAR) PPARdelta and PPARgamma agonist activity. The structure of the compounds of the invention are defined by Formula I below, wherein the various substituents are defined herein, including their physiologically acceptable salts. Processes for the compounds preparation are also disclosed. The compounds are suitable for the treatment of fatty acid metabolism and glucose utilization disorders, disorders relating to insulin resistance are involved as well as demyelinating and other neurodegenerative disorders of the central and peripheral nervous system.