The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 03, 2009
Filed:
Nov. 03, 2004
Jurgen G. Schmidt, Los Alamos, NM (US);
Anne E. Boyer, Atlanta, GA (US);
Suzanne R. Kalb, Atlanta, GA (US);
Hercules Moura, Tucker, GA (US);
John R. Barr, Suwannee, GA (US);
Adrian R. Woolfitt, Atlanta, GA (US);
Jurgen G. Schmidt, Los Alamos, NM (US);
Anne E. Boyer, Atlanta, GA (US);
Suzanne R. Kalb, Atlanta, GA (US);
Hercules Moura, Tucker, GA (US);
John R. Barr, Suwannee, GA (US);
Adrian R. Woolfitt, Atlanta, GA (US);
Los Alamos National Security, LLC, Los Alamos, NM (US);
Abstract
The present invention is directed to a method for detecting the presence of clostridial neurotoxins in a sample by mixing a sample with a peptide that can serve as a substrate for proteolytic activity of a clostridial neurotoxin; and measuring for proteolytic activity of a clostridial neurotoxin by a mass spectroscopy technique. In one embodiment, the peptide can have an affinity tag attached at two or more sites.