The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 03, 2009

Filed:

Dec. 24, 2003
Applicants:

Tatsuya Ohashi, Koriyama, JP;

Toshihide Miura, Koriyama, JP;

Yoshihiko Igarashi, Mibu, JP;

Fumio Nomura, Chiba, JP;

Takeshi Tomonaga, Chiba, JP;

Katsuhiro Katayama, Koriyama, JP;

Inventors:

Tatsuya Ohashi, Koriyama, JP;

Toshihide Miura, Koriyama, JP;

Yoshihiko Igarashi, Mibu, JP;

Fumio Nomura, Chiba, JP;

Takeshi Tomonaga, Chiba, JP;

Katsuhiro Katayama, Koriyama, JP;

Assignee:

Nitto Boseki Co., Ltd., Fukushima-Shi, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/543 (2006.01); G01N 33/546 (2006.01); G01N 33/573 (2006.01); C07K 16/40 (2006.01); C12P 21/08 (2006.01); C12N 5/20 (2006.01);
U.S. Cl.
CPC ...
Abstract

Using two types of antibodies, i.e., a first antibody having a higher affinity for a target substance than for a competitive substance and a second antibody having a higher affinity for the competitive substance than for the target substance, a specimen is treated with these two antibodies. Then, the competitive substance in the specimen first binds to the second antibody and thus the ratio of the target substance to the competitive substance in the specimen is enlarged. As a result, the target substance becomes liable to bind to the first antibody and, in its turn, the reactivity of the target substance is elevated compared with the case of using the first antibody alone. Thus, the target substance in the specimen can be accurately assayed while avoiding the effects of the competitive substance contained in the specimen.


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