The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 03, 2009

Filed:

Sep. 30, 2005
Applicants:

Jungbae Kim, Richland, WA (US);

Ja Hun Kwak, Richland, WA (US);

Jay W. Grate, West Richland, WA (US);

Inventors:

Jungbae Kim, Richland, WA (US);

Ja Hun Kwak, Richland, WA (US);

Jay W. Grate, West Richland, WA (US);

Assignee:

Battelle Memorial Institute, Richland, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/00 (2006.01); C12P 1/00 (2006.01); C12N 11/14 (2006.01); C12N 11/02 (2006.01); C12N 11/08 (2006.01); C12M 1/00 (2006.01); C12M 1/34 (2006.01); C12M 1/40 (2006.01);
U.S. Cl.
CPC ...
Abstract

A process for preparing high stability, high activity biocatalytic materials is disclosed and processes for using the same. The process involves coating of a material or fiber with enzymes and enzyme aggregate providing a material or fiber with high biocatalytic activity and stability useful in heterogeneous environments. In one illustrative approach, enzyme 'seeds' are covalently attached to polymer nanofibers followed by treatment with a reagent that crosslinks additional enzyme molecules to the seed enzymes forming enzyme aggregates thereby improving biocatalytic activity due to increased enzyme loading and enzyme stability. This approach creates a useful new biocatalytic immobilized enzyme system with potential applications in bioconversion, bioremediation, biosensors, and biofuel cells.


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