The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 03, 2009

Filed:

Oct. 14, 2005
Applicants:

David J. Anvar, Sunnyvale, CA (US);

David J. Chazan, Palo Alto, CA (US);

Bryan P. Flaherty, Half Moon Bay, CA (US);

Bhairavi R. Parikh, Palo Alto, CA (US);

Inventors:

David J. Anvar, Sunnyvale, CA (US);

David J. Chazan, Palo Alto, CA (US);

Bryan P. Flaherty, Half Moon Bay, CA (US);

Bhairavi R. Parikh, Palo Alto, CA (US);

Assignee:

Aperon Biosystems Corp., Menlo Park, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/497 (2006.01);
U.S. Cl.
CPC ...
Abstract

Highly sensitive devices for detecting nitric oxide and/or other gaseous analytes in gaseous samples are improved by the incorporation of a carbon monoxide scavenger in the interior of the device or in the device packaging. The release of carbon monoxide within the housing of the device by the plastic used in the construction of the housing or by anything within the device that releases carbon monoxide causes a loss in sensitivity due to competition between the carbon monoxide and the nitric oxide for the binding sites on the device sensor. The scavenger corrects this by either catalyzing the oxidation of carbon monoxide to the less competitive carbon dioxide or immobilizing the carbon monoxide by affinity-type or covalent binding. Analogous effects are achieved for analytes other than nitric oxide but that likewise encounter interference from carbon monoxide in binding to sensors.


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