The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 27, 2009
Filed:
Nov. 14, 2003
Bart Rudolf Romanie Kesteleyn, Berlare, BE;
Wim Van DE Vreken, Beveren, BE;
Natalie Maria Francisca Kindermans, Mechelen, BE;
Maxime Francis Jean-marie Ghislain Canard, La Hulpe, BE;
Kurt Hertogs, Antwerp, BE;
Eva Bettens, Zoersel, BE;
Veronique Corine Paul DE Vroey, Boechout, BE;
Dirk Edward Désiré Jochmans, Herent, BE;
Bart Rudolf Romanie Kesteleyn, Berlare, BE;
Wim Van De Vreken, Beveren, BE;
Natalie Maria Francisca Kindermans, Mechelen, BE;
Maxime Francis Jean-Marie Ghislain Canard, La Hulpe, BE;
Kurt Hertogs, Antwerp, BE;
Eva Bettens, Zoersel, BE;
Veronique Corine Paul De Vroey, Boechout, BE;
Dirk Edward Désiré Jochmans, Herent, BE;
Tibotec Pharmaceuticals Ltd., Little Island, Co. Cork, IE;
Abstract
The present invention concerns the compounds of formula (I) their N-oxides, salts, stereoisomeric forms, racemic mixtures, prodrugs, esters and metabolites, wherein n is 1, 2 or 3; Ris H, CN, halo, aminoC(═O), C(═O)OH, CalkyloxyC(═O), CalkylC(═O), mono- or di(Calkyl)aminoC(═O), arylaminoC(═O), N-(aryl)-N—(Calkyl)aminoC(═O), methanimidamidyl, N-hydroxy-methanimidamidyl, mono- or di(Calkyl)methanimidamidyl, Hetor Het; Ris H, Calkyl, Calkenyl, Ccycloalkyl, wherein said Calkyl, Calkenyl and Ccycloalkyl may be optionally substituted; Ris nitro, cyano, amino, halo, hydroxy, Calkyloxy, hydroxyC(═O), aminoC(═O), CalkyloxyC(═O), mono- or di(Calkyl)aminoC(═O), CalkylC(═O), methanimidamidyl, mono- or di(Calkyl)methanimidamidyl, N-hydroxy-methanimidamidyl or Het; for use as a medicine. The invention further relates to a novel subgroup of the compounds of formula (I), and to compositions comprising compounds of formula (I).