The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 27, 2009
Filed:
Dec. 28, 2004
Susan Kay Hoiseth, Montebello, NY (US);
Thomas Newell Metcalf, Iii, Wind Gap, PA (US);
Yury Vladimirovich Matsuka, New Windsor, NY (US);
Michael Hagen, Pittsford, NY (US);
Lakshmi Khandke, Nanuet, NY (US);
Susan Kay Hoiseth, Montebello, NY (US);
Thomas Newell Metcalf, III, Wind Gap, PA (US);
Yury Vladimirovich Matsuka, New Windsor, NY (US);
Michael Hagen, Pittsford, NY (US);
Lakshmi Khandke, Nanuet, NY (US);
Wyeth, Madison, NJ (US);
Abstract
The present invention provides a method for producing a less-painful immunogenic composition of a hydrophobic protein in a pharmaceutically acceptable carrier suitable for administering to a mammal, comprising the steps of (a) solubilizing said hydrophobic protein with a zwitterionic detergent to make a first composition; (b) altering said first composition, such that the altered composition produces a reduction in pain as measured in the rat footpad model as compared to said first composition.