The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 27, 2009
Filed:
Feb. 25, 2008
Applicants:
Isaac Ghebre-sellassie, Morris Plains, NJ (US);
Hibrenigus Terefe, Somerville, NJ (US);
Inventors:
Isaac Ghebre-Sellassie, Morris Plains, NJ (US);
Hibrenigus Terefe, Somerville, NJ (US);
Assignee:
Exxpharma, LLC, Somerville, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B02C 1/00 (2006.01); B02C 21/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The solubility/dissolution rate of a poorly soluble drug is enhanced by a process that utilizes a twin-screw extruder containing (i) a feed zone containing a first liquid and powder feed stations; (ii) a grinding/mixing zone containing a second liquid feed port located at an upstream portion of such zone; (iii) a granulation zone containing a second powder feed station located at an upstream portion of such zone and a third liquid feed port located at a downstream portion of such zone; and (iv) a wet milling zone.