The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 20, 2009

Filed:

Dec. 20, 2005
Applicants:

Peter David Gluckman, Auckland, NZ;

Gregory Brian Thomas, Western Australia, AU;

Jian Guan, Auckland, NZ;

Michael Dragunow, Auckland, NZ;

Ashmit Kumar Anand, Auckland, NZ;

Frank Sieg, Auckland, NZ;

Margaret Anne Brimble, Auckland, NZ;

Inventors:

Peter David Gluckman, Auckland, NZ;

Gregory Brian Thomas, Western Australia, AU;

Jian Guan, Auckland, NZ;

Michael Dragunow, Auckland, NZ;

Ashmit Kumar Anand, Auckland, NZ;

Frank Sieg, Auckland, NZ;

Margaret Anne Brimble, Auckland, NZ;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/401 (2006.01); C07D 207/16 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention provides analogs and peptidomimetics of glycyl-L-prolyl-L-glutamic acid (GPE). In particular, this invention relates to GPE analogs and peptidomimetics that are anti-apoptotic, anti-necrotic and have neuroprotective effects. These agents are useful in treating neurodegeneration and behavioural disorders caused by toxins, traumatic brain injury and autoimmune disorders of the brain, such as multiple sclerosis and in reducing seizures.


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