The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 20, 2009
Filed:
Sep. 02, 2005
Prabha N. Ibrahim, Mountain View, CA (US);
Ryan Bremer, Albany, CA (US);
Sam Gillette, Oakland, CA (US);
Hanna Cho, Oakland, CA (US);
Marika Nespi, Berkeley, CA (US);
Shumeye Mamo, Oakland, CA (US);
Chao Zhang, Moraga, CA (US);
Dean R. Artis, Kensington, CA (US);
Byunghun Lee, Marina, CA (US);
Rebecca Zuckerman, Alameda, CA (US);
Prabha N. Ibrahim, Mountain View, CA (US);
Ryan Bremer, Albany, CA (US);
Sam Gillette, Oakland, CA (US);
Hanna Cho, Oakland, CA (US);
Marika Nespi, Berkeley, CA (US);
Shumeye Mamo, Oakland, CA (US);
Chao Zhang, Moraga, CA (US);
Dean R. Artis, Kensington, CA (US);
Byunghun Lee, Marina, CA (US);
Rebecca Zuckerman, Alameda, CA (US);
Plexxikon, Inc., Berkeley, CA (US);
Abstract
Compounds are described that are active on PDE4. Also described are crystal structures of PDE4B determined using X-ray crystallography, the use of PDE4B crystals and structural information for identifying molecular scaffolds, for developing ligands that bind to and modulate PDE4B, and for identifying improved ligands based on known ligands.