The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 20, 2009
Filed:
Jul. 29, 2004
Melwyn Abreo, Jamul, CA (US);
Daniel F. Harvey, San Diego, CA (US);
Heinz W. Gschwend, Santa Rosa, CA (US);
Wenbao LI, San Diego, CA (US);
Chi Tu, San Diego, CA (US);
Rajender Kamboj, Burnaby, CA;
Michael D. Winther, Vancouver, CA;
Vishnumurthy Kodumuru, Burnaby, CA;
Cindy J. Hudson, Buena Park, CA (US);
Mikhail A. Kondratenko, San Diego, CA (US);
Shifeng Liu, Port Coquitlam, CA;
Vandna Raina, Vancouver, CA;
Serguei Sviridov, Burnaby, CA;
Zaihui Zhang, Vancouver, CA;
Mehran Seid Bagherzadeh, North Vancouver, CA;
Shaoyi Sun, Vancouver, CA;
Melwyn Abreo, Jamul, CA (US);
Daniel F. Harvey, San Diego, CA (US);
Heinz W. Gschwend, Santa Rosa, CA (US);
Wenbao Li, San Diego, CA (US);
Chi Tu, San Diego, CA (US);
Rajender Kamboj, Burnaby, CA;
Michael D. Winther, Vancouver, CA;
Vishnumurthy Kodumuru, Burnaby, CA;
Cindy J. Hudson, Buena Park, CA (US);
Mikhail A. Kondratenko, San Diego, CA (US);
Shifeng Liu, Port Coquitlam, CA;
Vandna Raina, Vancouver, CA;
Serguei Sviridov, Burnaby, CA;
Zaihui Zhang, Vancouver, CA;
Mehran Seid Bagherzadeh, North Vancouver, CA;
Shaoyi Sun, Vancouver, CA;
Xenon Pharmaceuticals Inc., Burnaby, British Columbia, CA;
Abstract
Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I): wherein: W is —O—, —N(R1)—, C(O), S(O)t; (where t is 0, 1 or 2), N(R1)S(O)2, S(O)2N(R1), C(O)N(R1) or N(R1)C(O)N(R1); and V is C(O), C(S), C(O)N(R1)—, C(O)O—, S(O)2—, S(O)2N(R1)— or C(R11)H; and x, y, R1, R2, R3, R4, R5, R6, R7, R7, R8, R8, R9, R9, R10 and R10are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.