The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 13, 2009
Filed:
Oct. 24, 2005
Applicants:
John Leo Considine, Bridgewater, NJ (US);
Galina Vid, New City, NY (US);
Zhixian Ding, Fort Lee, NJ (US);
Inventors:
John Leo Considine, Bridgewater, NJ (US);
Galina Vid, New City, NY (US);
Zhixian Ding, Fort Lee, NJ (US);
Assignee:
Wyeth, Madison, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 231/56 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention concerns processes for the production and purification of compounds of the formula: where R-Rare as defined in the specification. Preferred processes of the invention utilize a lithium bis(trimethylsilyl)amide, lithium dicyclohexylamide, or potassium bis(trimethylsilyl)amide base and a R—X alkylating agent where X is as described in the specification. An alcohol preferably is added to the product solution is used to promote crystallization of the desired product.