The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 13, 2009
Filed:
Mar. 24, 2005
Mark R. Andersen, Carlsbad, CA (US);
Kenneth J. Livak, San Jose, CA (US);
Adam Broomer, Foster City, CA (US);
Caifu Chen, Palo Alto, CA (US);
Mark R. Andersen, Carlsbad, CA (US);
Kenneth J. Livak, San Jose, CA (US);
Adam Broomer, Foster City, CA (US);
Caifu Chen, Palo Alto, CA (US);
Applied Biosystems, LLC, Carlsbad, CA (US);
Abstract
The present invention is directed to methods, reagents, and kits for detecting the presence or absence of (or quantifying) target polynucleotide sequences and proteins in at least one sample using encoding and decoding reactions. When a particular target polynucleotide is present in a sample for example, a reaction product is formed in the encoding reaction that includes addressable primer portions. At least one labeling probe and at least one address primer can be employed in the decoding amplification reaction thereby providing a detectable signal value depending upon whether a sequence is present or absent. In some embodiments, the encoding comprises a ligation reaction with linker probes, and single nucleotide polymorphisms (SNPs) are analyzed.