The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 06, 2009

Filed:

Aug. 08, 2006
Applicants:

Guojie Ho, Sudbury, MA (US);

Darren J. Carrozzella, Cambridge, MA (US);

Inventors:

Guojie Ho, Sudbury, MA (US);

Darren J. Carrozzella, Cambridge, MA (US);

Assignee:

Millenium Pharmaceuticals, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention provides a method for making maytansinoids having a chiral amino acid side chain, such as DM1 and DM4 that are used to treat cancer. According to this method, the side chain may be added with little epimerization of the amino acid chiral center.


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Ho, Guojie. (2009). Method of acylating maytansinol with chiral amino acids (U.S. Patent No. 7598375). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7598375

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