The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 06, 2009
Filed:
Oct. 10, 2002
Emilio A. Emini, Wayne, PA (US);
David C. Kaslow, Rancho Santa Fe, CA (US);
Andrew J. Bett, Lansdale, PA (US);
John W. Shiver, Chalfont, PA (US);
Alfredo Nicosia, Rome, IT;
Armin Lahm, Rome, IT;
Alessandra Luzzago, Rome, IT;
Riccardo Cortese, Rome, IT;
Stefano Colloca, Rome, IT;
Emilio A. Emini, Wayne, PA (US);
David C. Kaslow, Rancho Santa Fe, CA (US);
Andrew J. Bett, Lansdale, PA (US);
John W. Shiver, Chalfont, PA (US);
Alfredo Nicosia, Rome, IT;
Armin Lahm, Rome, IT;
Alessandra Luzzago, Rome, IT;
Riccardo Cortese, Rome, IT;
Stefano Colloca, Rome, IT;
Merck & Co., Inc., Rahway, NJ (US);
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.p.A., Rome, IT;
Abstract
The present invention features Ad6 vectors and a nucleic acid encoding a Met-NS3-NS4A-NS4B-NS5A-NS5B polypeptide containing an inactive NS5B RNA-dependent RNA polymerase region. The nucleic acid is particularly useful as a component of an adenovector or DNA plasmid vaccine providing a broad range of antigens for generating an HCV specific cell mediated immune (CMI) response against HCV.