The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 06, 2009
Filed:
May. 01, 2003
Kazuo Kubo, Takasaki, JP;
Hiroaki Ohno, Takasaki, JP;
Toshiyuki Isoe, Shibuya-ku, JP;
Tuyoshi Nishitoba, Shibuya-ku, JP;
Kazuo Kubo, Takasaki, JP;
Hiroaki Ohno, Takasaki, JP;
Toshiyuki Isoe, Shibuya-ku, JP;
Tuyoshi Nishitoba, Shibuya-ku, JP;
Kirin Beer Kabushiki Kaisha, Tokyo-To, JP;
Abstract
An objective of the present invention is to provide compounds which have inhibitory activity against autophosphorylation of macrophage colony-stimulating factor receptors. The compounds of the present invention are represented by formula (I) and salt and solvate thereof: wherein X represents CH or N; Z represents O or S; R, R, and Rrepresent H, optionally substituted alkoxy or the like; Rrepresents H; R, R, R, and Rrepresent H, halogen, alkyl, alkoxy, trifluoromethyl or the like; Rand Rrepresent H, alkyl or the like; and any one of Rand Rrepresents H with the other representing alkyl and Rrepresents an optionally substituted carbocyclic or heterocyclic ring or the like, or Rrepresents H and Rand Rcombine together to form a bicyclic carbocyclic ring.