The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 06, 2009
Filed:
Jun. 04, 2004
Applicants:
Hema S. Sista, Cupertino, CA (US);
Yero J. Espinoza, Alameda, CA (US);
Inventors:
Hema S. Sista, Cupertino, CA (US);
Yero J. Espinoza, Alameda, CA (US);
Assignee:
Genzyme Corporation, Framingham, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/01 (2006.01); C12N 1/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
Stable pharmaceutical compositions comprising recombinant adeno-associated virus (AAV) virions are described. The compositions provide protection against loss of recombinant AAV vector genomes and transduceability under conditions such as exposure to cycles of freezing and thawing and storage in glass or polypropylene vials. The compositions comprise recombinant AAV virions in combination with one or more dihydric or polyhydric alcohols, and, optionally, a detergent, such as a sorbitan ester. Also described are methods of using the compositions.