The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 06, 2009

Filed:

Jan. 02, 2008
Applicants:

Wei-heng Shih, Bryn Mawr, PA (US);

Wan Y. Shih, Bryn Mawr, PA (US);

Hui LI, Philadelphia, PA (US);

Melissa Colleen Schillo, Broadview Heights, OH (US);

Inventors:

Wei-Heng Shih, Bryn Mawr, PA (US);

Wan Y. Shih, Bryn Mawr, PA (US);

Hui Li, Philadelphia, PA (US);

Melissa Colleen Schillo, Broadview Heights, OH (US);

Assignee:

Drexel University, Philadelphia, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C01B 17/20 (2006.01); C01G 21/21 (2006.01); C01G 11/02 (2006.01); C01G 9/08 (2006.01); C01G 45/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

An economic, direct synthetic method for producing water soluble QDs that are ready for bioconjugation is provided. The method can produce aqueous QDs with emission wavelengths varying from 400 nm to 700 nm. Highly luminescent metal sulfide (MS) QDs are produced via an aqueous synthesis route. MS QDs are capped with thiol-containing charged molecules in a single step. The resultant MS QDs exhibit the distinctive excitonic photoluminescence desired of QDs and can be fabricated to avoid undesirable broadband emissions at higher wavelengths. This provides a significant improvement over the present complex and expensive commercial processes for the production of QDs. The aqueous QDs are stable in biological fluids over a long period of time. In addition, nontoxic ZnS QDs have been produced with good photoluminescence properties by refluxing the ZnS QD suspensions over a period of time.


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