The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 29, 2009
Filed:
Dec. 16, 2002
Jan G. J. Van DE Winkel, Zeist, NL;
Marcus A. Van Dijk, Bilthoven, NL;
Edward Halk, Sunnyvale, CA (US);
Arnout F. Gerritsen, Bunnik, NL;
Jørgen Petersen, Rungsted Kyst, DK;
Ole Baadsgaard, Malmo, SE;
Jan G. J. van de Winkel, Zeist, NL;
Marcus A. van Dijk, Bilthoven, NL;
Edward Halk, Sunnyvale, CA (US);
Arnout F. Gerritsen, Bunnik, NL;
Jørgen Petersen, Rungsted Kyst, DK;
Ole Baadsgaard, Malmo, SE;
Genmab A/S, Copenhagen, DK;
Abstract
Isolated human monoclonal antibodies which specifically bind to human EGFR, and related antibody-based compositions and molecules, are disclosed. The human antibodies can be produced by a transfectoma or in a non-human transgenic animal, e.g., a transgenic mouse, capable of producing multiple isotypes of human monoclonal antibodies by undergoing V-D-J recombination and isotype switching. Also disclosed are pharmaceutical compositions comprising the human antibodies, non-human transgenic animals and hybridomas which produce the human antibodies, and therapeutic and diagnostic methods for using the human antibodies.