The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 29, 2009
Filed:
Aug. 17, 2007
Jennifer Rebecca Allen, Indianapolis, IN (US);
Albert Kudzovi Amegadzie, Indianapolis, IN (US);
Kevin Matthew Gardinier, Indianapolis, IN (US);
George Stuart Gregory, Fishers, IN (US);
Stephen Andrew Hitchcock, Westlake Village, CA (US);
Paul J. Hoogestraat, Indianapolis, IN (US);
Winton Dennis Jones, Jr., Carmel, IN (US);
Daryl Lynn Smith, Fishers, IN (US);
Jennifer Rebecca Allen, Indianapolis, IN (US);
Albert Kudzovi Amegadzie, Indianapolis, IN (US);
Kevin Matthew Gardinier, Indianapolis, IN (US);
George Stuart Gregory, Fishers, IN (US);
Stephen Andrew Hitchcock, Westlake Village, CA (US);
Paul J. Hoogestraat, Indianapolis, IN (US);
Winton Dennis Jones, Jr., Carmel, IN (US);
Daryl Lynn Smith, Fishers, IN (US);
Eli Lilly and Company, Indianapolis, IN (US);
Abstract
Novel compounds of structural formula (I) are disclosed. As modulators of the Cannabinoid-1 (CB1) receptor, these compounds are useful in the treatment, prevention and suppression of diseases mediated by the CB1 receptor. As such, compounds of the present invention are useful as in the treatment, prevention and suppression of psychosis, memory deficits, cognitive disorders, migraine, neuropathy, neuro-inflammatory disorders (e.g., multiple sclerosis, Guillain-Barre syndrome and the inflammatory sequelae of viral encephalitis), cerebral vascular accidents, head trauma, anxiety disorders, stress, epilepsy, Parkinson's disease, and schizophrenia. The compounds are also useful for the treatment of substance abuse disorders, particularly to opiates, alcohol, and nicotine. The compounds are also useful for the treatment of obesity or eating disorders associated with excessive food intake and complications associated therewith.