The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 29, 2009

Filed:

Feb. 06, 2006
Applicants:

Michael J. Breslin, Drexel Hill, PA (US);

Paul J. Coleman, Wallingford, PA (US);

Christopher D. Cox, Harleysville, PA (US);

Lou Anne Neilson, Sellersville, PA (US);

David B. Whitman, Phoenixville, PA (US);

Inventors:

Michael J. Breslin, Drexel Hill, PA (US);

Paul J. Coleman, Wallingford, PA (US);

Christopher D. Cox, Harleysville, PA (US);

Lou Anne Neilson, Sellersville, PA (US);

David B. Whitman, Phoenixville, PA (US);

Assignee:

Merck & Co. Inc., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4162 (2006.01); C07D 231/54 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to tricyclic pyrazoles that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also relates to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.


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