The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 29, 2009
Filed:
Jan. 24, 2005
Andrei Konradi, Burlingame, CA (US);
Michael A. Pleiss, Sunnyvale, CA (US);
Jenifer L. Smith, San Francisco, CA (US);
Christopher M. Semko, Fremont, CA (US);
Chris Vandevert, San Francisco, CA (US);
Andrei Konradi, Burlingame, CA (US);
Michael A. Pleiss, Sunnyvale, CA (US);
Jenifer L. Smith, San Francisco, CA (US);
Christopher M. Semko, Fremont, CA (US);
Chris Vandevert, San Francisco, CA (US);
Elan Pharmaceuticals, Inc., S. San Francisco, CA (US);
Abstract
Disclosed are conjugates which bind VLA-4. Certain of these conjugates also inhibit leukocyte adhesion and, in particular, leukocyte adhesion mediated by VLA-4. Such conjugates are useful in the treatment of inflammatory diseases in a mammalian patient, e.g., human, such as asthma, Alzheimer's disease, atherosclerosis, AIDS dementia, diabetes, inflammatory bowel disease, rheumatoid arthritis, tissue transplantation, tumor metastasis and myocardial ischemia. The conjugates can also be administered for the treatment of inflammatory brain diseases such as multiple sclerosis.