The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 29, 2009
Filed:
Apr. 05, 2007
Jingwu Duan, Yardley, PA (US);
Bin Jiang, Norristown, PA (US);
Lihua Chen, Boothwyn, PA (US);
Zhonghui LU, King of Prussia, PA (US);
Joseph Barbosa, Lambertville, NJ (US);
William J. Pitts, Newtown, PA (US);
Jingwu Duan, Yardley, PA (US);
Bin Jiang, Norristown, PA (US);
Lihua Chen, Boothwyn, PA (US);
Zhonghui Lu, King of Prussia, PA (US);
Joseph Barbosa, Lambertville, NJ (US);
William J. Pitts, Newtown, PA (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
Abstract
The present application describes novel barbituric acid derivatives of formula I: or pharmaceutically acceptable salt or prodrug forms thereof, wherein A, B, L, R, R, R, R, R, n, W, U, X, Y, Z, U, X, Y, and Zare defined in the present specification, which are useful as TNF-α converting enzyme (TACE) and matrix metalloproteinases (MMP) inhibitors.