The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 29, 2009
Filed:
Aug. 14, 2001
Applicants:
Hrvoje Petkovic, Cambridge, GB;
Steven Gary Kendrew, Cambridge, GB;
Peter Francis Leadlay, Cambridge, GB;
Inventors:
Hrvoje Petkovic, Cambridge, GB;
Steven Gary Kendrew, Cambridge, GB;
Peter Francis Leadlay, Cambridge, GB;
Assignee:
Biotica Technology Limited, Cambridgeshire, GB;
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/60 (2006.01); C07K 19/00 (2006.01); C12N 15/52 (2006.01);
U.S. Cl.
CPC ...
Abstract
Biosyntheses of compounds whereof at least portions are polyketides produced by means of polyketide synthase (PKS) enzyme complexes are carried out after specific alterations have been made within the acyltransferase (AT) domains of the PKSs. Particular motifs in or near the substrate binding pocket are disclosed, such that alterations therein affect substrate specificity.