The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 29, 2009

Filed:

Jul. 03, 2006
Applicants:

Peter S. LU, Palo Alto, CA (US);

Michael P. Belmares, San Jose, CA (US);

Dave Garman, San Jose, CA (US);

Inventors:

Peter S. Lu, Palo Alto, CA (US);

Michael P. Belmares, San Jose, CA (US);

Dave Garman, San Jose, CA (US);

Assignee:

Arbor Vita Corporation, Sunnyvale, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/70 (2006.01); G01N 33/53 (2006.01); G01N 33/542 (2006.01); G01N 33/00 (2006.01); C12M 1/34 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides method and compositions for determining the presence and amount of an influenza virus in a sample including high risk strains of Influenza A. Also provided are methods for determining whether a subject is infected with a influenza virus, as well as, the type and strain of the influenza virus. The methods involve contacting a sample from the subject with a PDZ polypeptides (PDZ) and/or PDZ ligands (PL) and determining whether binding interactions occur between PDZ and PL. Assays for identifying anti-viral agents are also provided, as well as, methods for using the compositions to alter PDZ binding to PL in influenza infected cells.


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