The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 22, 2009

Filed:

Sep. 27, 2005
Applicants:

Oded Arad, Rechovot, IL;

Lior Zelikovitch, Mazkeret Batia, IL;

Mohammed Alnabari, Hura, IL;

Michael Brand, RaAnana, IL;

Irina Gribun, Bat-Yam, IL;

Ada Salman, Ramat-Gan, IL;

Meital Shiffer, Tel Aviv, IL;

Moty Shookrun, Petach-Tikva, IL;

Orna Kurlat, Beer-Sheba, IL;

Moshe Bentolila, Moshav Tkuma, IL;

Joseph Kaspi, Givatayim, IL;

Inventors:

Oded Arad, Rechovot, IL;

Lior Zelikovitch, Mazkeret Batia, IL;

Mohammed Alnabari, Hura, IL;

Michael Brand, RaAnana, IL;

Irina Gribun, Bat-Yam, IL;

Ada Salman, Ramat-Gan, IL;

Meital Shiffer, Tel Aviv, IL;

Moty Shookrun, Petach-Tikva, IL;

Orna Kurlat, Beer-Sheba, IL;

Moshe Bentolila, Moshav Tkuma, IL;

Joseph Kaspi, Givatayim, IL;

Assignee:

Chemagis Ltd., Bnei-Brak, IL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 211/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a crystalline donepezil maleate, which is used as an intermediate in the preparation of donepezil hydrochloride. Also provided are novel processes for producing same in substantially pure form and a process for producing pharmaceutically pure amorphous donepezil hydrochloride therefrom.


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