The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 22, 2009
Filed:
May. 30, 2006
Jonathan Zalevsky, Riverside, CA (US);
Duc-hanh Thi Nguyen, Sylmar, CA (US);
Gregory L. Moore, Monrovia, CA (US);
Sergei A. Ezhevsky, San Diego, CA (US);
John R. Desjarlais, Pasadena, CA (US);
Arthur J. Chirino, Camarillo, CA (US);
Darian Cash, Los Angeles, CA (US);
Matthew J. Bernett, Monrovia, CA (US);
Jonathan Zalevsky, Riverside, CA (US);
Duc-Hanh Thi Nguyen, Sylmar, CA (US);
Gregory L. Moore, Monrovia, CA (US);
Sergei A. Ezhevsky, San Diego, CA (US);
John R. Desjarlais, Pasadena, CA (US);
Arthur J. Chirino, Camarillo, CA (US);
Darian Cash, Los Angeles, CA (US);
Matthew J. Bernett, Monrovia, CA (US);
Xencor, Inc., Monrovia, CA (US);
Abstract
An adiponectin variant with one or more amino acid modifications relative to a corresponding parent adiponectin, wherein the adiponectin variant is not glycosylated, the adiponectin variant does not have residues 1-100 relative to human adiponectin, and wherein the solubility of the variant is improved by at least 3-fold relative to residues 110-244 of human adiponectin.