The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 22, 2009

Filed:

Sep. 23, 2004
Applicants:

Srikanth Venkatraman, Woodbridge, NJ (US);

F. George Njoroge, Warren, NJ (US);

Wanli Wu, Edison, NJ (US);

Viyyoor M. Girijavallabhan, Parsippany, NJ (US);

Brian Mckittrick, New Vernon, NJ (US);

Jing Su, Scotch Plains, NJ (US);

Francisco Velazquez, Clinton, NJ (US);

Patrick A. Pinto, Morris Plains, NJ (US);

Inventors:

Srikanth Venkatraman, Woodbridge, NJ (US);

F. George Njoroge, Warren, NJ (US);

Wanli Wu, Edison, NJ (US);

Viyyoor M. Girijavallabhan, Parsippany, NJ (US);

Brian McKittrick, New Vernon, NJ (US);

Jing Su, Scotch Plains, NJ (US);

Francisco Velazquez, Clinton, NJ (US);

Patrick A. Pinto, Morris Plains, NJ (US);

Assignee:

Schering Corporation, Kenilworth, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/12 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention discloses novel compounds which have HCV protease inhibitory activity as well as pharmaceutical compositions comprising such compounds and methods of using them to treat disorders associated with the HCV protease. The novel compounds typically include a 15-20 member macrocycle and have the general structure of structural Formula 1: wherein Z', L′, M′, R, X and D are defined herein.


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