The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 22, 2009
Filed:
Feb. 22, 2006
Ana I. Jiménez, Madrid, ES;
Angela Sesto, Madrid, ES;
Irene Gascón, Madrid, ES;
José P. Román, Vitoria, ES;
Gonzalo González DE Buitrago, Madrid, ES;
Ana I. Jiménez, Madrid, ES;
Angela Sesto, Madrid, ES;
Irene Gascón, Madrid, ES;
José P. Román, Vitoria, ES;
Gonzalo González de Buitrago, Madrid, ES;
Sylentis S.A.U., Madrid, ES;
Abstract
The present invention relates to methods and compositions that decrease intraocular pressure (IOP) of the eye. The compositions of the invention comprise short interfering nucleic acid molecules (siNA) including, but not limited to, siRNA that decrease expression of genes associated with production or drainage of intraocular fluid. The compositions of the invention can be used in the preparation of a medicament for the treatment of an eye conditions displaying increased IOP such as glaucoma, infection, inflammation, uveitis, and diabetic retinopathy. The methods of the invention comprise the administration to a patient in need thereof an effective amount of one or more siNAs of the invention.