The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 22, 2009
Filed:
Jun. 06, 2007
Applicants:
Samuel Zalipsky, Redwood City, CA (US);
Radwan Kiwan, Albany, CA (US);
Inventors:
Samuel Zalipsky, Redwood City, CA (US);
Radwan Kiwan, Albany, CA (US);
Assignee:
Alza Corporation, Mountain View, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 37/18 (2006.01); A61K 38/00 (2006.01); C08B 11/00 (2006.01); C25D 3/60 (2006.01); A61K 9/127 (2006.01);
U.S. Cl.
CPC ...
Abstract
A conjugate comprised of a hydrophilic polymer covalently yet reversibly linked to a amine-, hydroxy- or carboxyl-containing ligand is described. The resulting conjugate is capable of releasing the parent amine, hydroxy, or carboxyl-containing compound via thiol-mediated cleavage. The system allows for delivery of various amino-, hydroxy-, or carboxy-containing drugs in the form of their thiolytically cleavable macromolecular conjugates.