The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 15, 2009
Filed:
Jun. 09, 2004
Yasumasa Hamada, Chiba, JP;
Tomoyuki Hasegawa, Sakai-gun, JP;
Toshiaki Matsui, Sakai-gun, JP;
Eiji Kasamatsu, Sakai-gun, JP;
Yasumasa Hamada, Chiba, JP;
Tomoyuki Hasegawa, Sakai-gun, JP;
Toshiaki Matsui, Sakai-gun, JP;
Eiji Kasamatsu, Sakai-gun, JP;
Ono Pharmaceutical Co., Ltd., Osaka, JP;
Abstract
The present invention relates to a process for producing (2R)-2-propyloctanoic acid, which comprises subjecting (2R)-2-hexyloxirane to a two-carbon adding reaction with ring-opening reaction, followed by a protecting reaction of a hydroxyl group to convert it to a compound represented by formula (I): (wherein X represents an optionally protected hydroxyl group) and then subjecting the compound to a one-carbon adding reaction to convert it to (2R)-2-propyloctanamide, followed by recrystallization and hydrolysis. According to the process of the present invention, (2R)-2-propyloctanoic acid can be produced by less steps as compared with the conventional method without a dangerous reaction.