The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 15, 2009

Filed:

Dec. 08, 2004
Applicants:

Andrew M. K. Pennell, San Francisco, CA (US);

James B. Aggen, Burlingame, CA (US);

J. J. Kim Wright, Redwood City, CA (US);

Subhabrata Sen, Sunnyvale, CA (US);

Brian E. Mcmaster, Mountain View, CA (US);

Daniel Joseph Dairaghi, Palo Alto, CA (US);

Wei Chen, Fremont, CA (US);

Penglie Zhang, Foster City, CA (US);

Inventors:

Andrew M. K. Pennell, San Francisco, CA (US);

James B. Aggen, Burlingame, CA (US);

J. J. Kim Wright, Redwood City, CA (US);

Subhabrata Sen, Sunnyvale, CA (US);

Brian E. McMaster, Mountain View, CA (US);

Daniel Joseph Dairaghi, Palo Alto, CA (US);

Wei Chen, Fremont, CA (US);

Penglie Zhang, Foster City, CA (US);

Assignee:

ChemoCentryx, Inc., Mountain View, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2006.01); C07D 401/14 (2006.01); C07D 403/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally aryl piperazine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.


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