The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 15, 2009
Filed:
Feb. 16, 2001
Ming-ming Zhou, Greenwich, CT (US);
Aneel K. Aggarwal, Edgewater, NJ (US);
Eric Verdin, San Francisco, CA (US);
Melanie Ott, San Francisco, CA (US);
Ming-Ming Zhou, Greenwich, CT (US);
Aneel K. Aggarwal, Edgewater, NJ (US);
Eric Verdin, San Francisco, CA (US);
Melanie Ott, San Francisco, CA (US);
J. David Gladstone Institutes, Irvine, CA (US);
Mt. Sinai School of Medicine, New York, NY (US);
Abstract
The present invention provides the structural determination of a bromodomain determined by NMR spectroscopy. The present invention also provides binding partners for the bromodomain. The present invention further provides the structural determination of the Tat-P/CAF binding complex determined by NMR spectroscopy. In addition, the present invention provides methodology for related drug discovery using high throughput drug screening or structure based rational drug design using the three-dimensional data.