The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7589124 B1

PDF
Full Text
Expired
Date of Patent:
Sep. 15, 2009

Filed:

Apr. 04, 2007
Applicants:

L. Gordon Letts, Dover, MA (US);

David S. Garvey, Dover, MA (US);

Inventors:

L. Gordon Letts, Dover, MA (US);

David S. Garvey, Dover, MA (US);

Assignee:

NicOx, S.A., , FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/34 (2006.01); C07C 229/42 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides novel nitrosated and/or nitrosylated cyclooxygenase 2 (COX-2) selective inhibitors and novel compositions and kits comprising at least one nitrosated and/or nitrosylated cyclooxygenase 2 (COX-2) selective inhibitor, and, optionally, at least one compound that donates, transfers or releases nitric oxide, stimulates endogenous synthesis of nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor or is a substrate for nitric oxide synthase, and/or, optionally, at least one therapeutic agent. The invention also provides methods for treating inflammation, pain and fever; for treating and/or improving the gastrointestinal properties of COX-2 selective inhibitors; for facilitating wound healing; for treating and/or preventing renal and/or respiratory toxicity; for treating and/or preventing other disorders resulting from elevated levels of cyclooxygenase-2; and for improving the cardiovascular profile of COX-2 selective inhibitors.


Find Patent Forward Citations

Letts, L.. (2009). Nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use (U.S. Patent No. 7589124). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7589124

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