The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 15, 2009
Filed:
Jun. 20, 2008
Beatrix Merla, Aachen, DE;
Stefan Oberboersch, Aachen, DE;
Bernd Sundermann, Aachen, DE;
Werner Englberger, Stolberg, DE;
Hagen-heinrich Hennies, Simmerath, DE;
Heinz Graubaum, Erkner, DE;
Beatrix Merla, Aachen, DE;
Stefan Oberboersch, Aachen, DE;
Bernd Sundermann, Aachen, DE;
Werner Englberger, Stolberg, DE;
Hagen-Heinrich Hennies, Simmerath, DE;
Heinz Graubaum, Erkner, DE;
Gruenenthal GmbH, Aachen, DE;
Abstract
Substituted oxadiazole compounds corresponding to formula I: in which X denotes CH, CH, CH═CH, CHCH, CHCH═CH or CHCHCH; Rdenotes aryl or heteroaryl, in each case unsubstituted or mono- or polysubstituted; or a Calkyl group-linked aryl or heteroaryl group, in each case unsubstituted or mono- or polysubstituted; Rdenotes aryl or heteroaryl, in each case unsubstituted or mono- or polysubstituted; a Calkyl chain-attached aryl group, in each case unsubstituted or mono- or polysubstituted; and Rand Rindependently denote H; Calkyl, in each case saturated or unsaturated, branched or unbranched, wherein Rand Rdo not simultaneously mean H; or Rand Rtogether denote CHCHOCHCH, or (CH). The compounds have an affinity for the μ-opioid receptor and may take the form of the racemate; enantiomers, diastereomers, mixtures of enantiomers or diastereomers, an individual enantiomer or diastereomer, a free base, or a salt with a physiologically acceptable acid.