The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 15, 2009

Filed:

Feb. 10, 2006
Applicants:

Nicholas D. P. Cosford, San Diego, CA (US);

Mark E. Layton, Harleysville, PA (US);

Jun Liang, Palo Alto, NJ (US);

Craig W. Lindsley, Schwenksville, PA (US);

Philip E. Sanderson, Valley Forge, PA (US);

Zhijian Zhao, Wilmington, DE (US);

Inventors:

Nicholas D. P. Cosford, San Diego, CA (US);

Mark E. Layton, Harleysville, PA (US);

Jun Liang, Palo Alto, NJ (US);

Craig W. Lindsley, Schwenksville, PA (US);

Philip E. Sanderson, Valley Forge, PA (US);

Zhijian Zhao, Wilmington, DE (US);

Assignee:

Merck & Co., Inc., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/04 (2006.01); A01N 43/58 (2006.01); A01N 43/42 (2006.01); A61K 31/70 (2006.01); A61K 31/50 (2006.01); A61K 31/495 (2006.01); A61K 31/52 (2006.01); A61K 31/47 (2006.01); C07D 487/00 (2006.01); C07D 491/00 (2006.01); C07H 15/00 (2006.01); C07H 17/00 (2006.01); C07H 17/02 (2006.01); C09B 25/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The instant invention provides for compounds that inhibit Akt activity. In particular, the compounds disclosed selectively inhibit one or two of the Akt isoforms. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting Akt activity by administering the compound to a patient in need of treatment of cancer.


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