The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 15, 2009
Filed:
Jul. 18, 2005
Georges Natsoulis, Kensington, CA (US);
Mark Fielden, Moutain View, CA (US);
Kurt Jarnagin, San Mateo, CA (US);
Kyle Kolaja, San Mateo, CA (US);
Georges Natsoulis, Kensington, CA (US);
Mark Fielden, Moutain View, CA (US);
Kurt Jarnagin, San Mateo, CA (US);
Kyle Kolaja, San Mateo, CA (US);
Entelos, Inc., Foster City, CA (US);
Abstract
The invention discloses reagent sets and gene signatures for predicting onset of renal tubule injury in a subject. The invention also provides a necessary set of 186 genes useful for generating signatures of varying size and performance capable of predicting onset of renal tubule injury. The invention also provides methods, apparatuses and reagents useful for predicting future renal tubule injury based on expression levels of genes in the signatures. In one particular embodiment the invention provides a method for predict whether a compound will induce renal tubule injury using gene expression data from sub-acute treatments.