The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 15, 2009

Filed:

Aug. 19, 2005
Applicants:

Linda Jeannine Brady, Gainesville, FL (US);

Kyle N. Seifert, Harrisonburg, VA (US);

Elisabeth E. Adderson, Memphis, TN (US);

John F. Bohnsack, Salt Lake City, UT (US);

Inventors:

Linda Jeannine Brady, Gainesville, FL (US);

Kyle N. Seifert, Harrisonburg, VA (US);

Elisabeth E. Adderson, Memphis, TN (US);

John F. Bohnsack, Salt Lake City, UT (US);

Assignees:

St. Jude Children's Research Hospital, Memphis, TN (US);

University of Florida, Gainesville, FL (US);

University of Utah Research Foundation, Salt Lake City, UT (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/09 (2006.01); C07K 14/315 (2006.01); C07H 21/04 (2006.01); C12P 21/04 (2006.01); C12N 15/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a group B(GBS) surface antigen, designated epsilon antigen, that is co-expressed with the delta antigen on a subset of serotype III GBS. Epsilon is expressed on more pathogenic Restriction Digest Pattern (RDP) III-3 GBS, but not on RDP types 1, 2, or 4. Accordingly, the present invention provides compositions and methods for detecting a group Bserotype III, RDP III-3 strain. Vaccines and methods of identifying agents which inhibit adhesion of a group Bcell to a host cell are also provided.


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