The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 15, 2009
Filed:
Feb. 27, 2003
Avindra Nath, Ellicott City, MD (US);
Russell J. Mumper, Lexington, KY (US);
Jerold Woodward, Lexington, KY (US);
Zhengrong Cui, Lexington, KY (US);
Avindra Nath, Ellicott City, MD (US);
Russell J. Mumper, Lexington, KY (US);
Jerold Woodward, Lexington, KY (US);
Zhengrong Cui, Lexington, KY (US);
University of Kentucky Research Foundation, Lexington, KY (US);
Abstract
Non-denatured, recombinant human immunodeficiency virus (HIV) Tat that is free of bacterial RNA and endotoxin is employed in an anti-HIV vaccine. A process of producing the recombinant Tat protein includes steps for removing bacterial RNA from the recombinant Tat and for removing endotoxin from the recombinant Tat protein. A Tat-adsorbed nanoparticle formulation and method of making the same. A method of vaccinating against and/or treating HIV infection comprises administering to a subject in need of such vaccination or treatment an immune-response inducing effective amount of the recombinant Tat protein.