The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 08, 2009
Filed:
Dec. 11, 2003
Markley C. Leavitt, Watkinsville, GA (US);
Jeff Rapp, Athens, GA (US);
Robert Ivarie, Watkinsville, GA (US);
Arthur Karnuah, Athens, GA (US);
Markley C. Leavitt, Watkinsville, GA (US);
Jeff Rapp, Athens, GA (US);
Robert Ivarie, Watkinsville, GA (US);
Arthur Karnuah, Athens, GA (US);
Synageva BioPharma Corp., Waltham, MA (US);
University of Georgia Research Foundation, Inc., Athens, GA (US);
Abstract
The present invention provides isolated and recombinant avian nucleic acid molecules comprising at least one avian MAR and an avian nucleic acid sequence encoding an ovalbumin transcriptional regulatory region. The isolated nucleic acid of the present invention is useful for reducing chromosomal positional effects upon the transcription of a transgene operably linked to the ovalbumin transcriptional regulatory region and transfected into a recipient avian cell The recombinant nucleic acid molecules of the present invention may further comprise a polyadenylation signal sequence or an avian 3' domain, and optionally, an internal ribosome entry site for expression of an operably linked heterologous nucleic acid insert in a transfected avian cell.