The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 08, 2009
Filed:
Jul. 10, 2002
Giuseppe D'alessio, Naples, IT;
Renata Piccoli, Naples, IT;
Claudia DE Lorenzo, Naples, IT;
Donald Balfour Palmer, Wembley, Middelsex, GB;
Mary Alice Ritter, London, GB;
Giuseppe D'Alessio, Naples, IT;
Renata Piccoli, Naples, IT;
Claudia De Lorenzo, Naples, IT;
Donald Balfour Palmer, Wembley, Middelsex, GB;
Mary Alice Ritter, London, GB;
Biotechnol S.A., Oeiras, PT;
Abstract
The invention refers to a fully human miniantibody (scFv), called Erbicin, specific for the receptor ErbB2, with a pharmacological, in particular antitumour, activity. It has been obtained from a larger fagmidic library (Griffin 1.) (19) of human synthetic scFv by panning (affinity selection on antigen) carried out on live cells that express various levels of ErbB2. The invention relates also to the DNA and aniino acid sequences of said antibody, to the procedure for isolating it, to its use in therapy.