The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 08, 2009
Filed:
Oct. 24, 2006
Xiaozhuang Bian, Dalian, CN;
Chengqiu Wang, Tianjin, CN;
MI He, Wuxue, CN;
Dexian Dou, Livonia, MI (US);
Xiaozhuang Bian, Dalian, CN;
Chengqiu Wang, Tianjin, CN;
Mi He, Wuxue, CN;
Dexian Dou, Livonia, MI (US);
Geneblue Corporation, Los Angeles, CA (US);
Abstract
Chromatin peptide drug molecules, which can block human cell hypoxia responsive pathway, are DNA affinity structural domain of related transcription genes or their imitating molecules or derivatives, containing 5-100 amino acid residues which can specifically bind firmly to HIF-1α gene self promoter or its downstream regulated more than 40 gene promoters. The above-mentioned molecules can permanently shut down molecular pathway including cell glucolysis reaction, immuno-inflammation reaction or hypoxia response, thus sustained stop uncontrollable proliferation of later stage tumor cells or chronic inflammation cells in the condition of hypoxia.