The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 2009

Filed:

Jun. 10, 2004
Applicants:

Takahiro Kuramochi, Chuo-ku, JP;

Norio Asai, Chuo-ku, JP;

Kazuhiro Ikegai, Chuo-ku, JP;

Seijiro Akamatsu, Chuo-ku, JP;

Hironori Harada, Chuo-ku, JP;

Noriko Ishikawa, Chuo-ku, JP;

Shohei Shirakami, Chuo-ku, JP;

Satoshi Miyamoto, Chuo-ku, JP;

Toshihiro Watanabe, Chuo-ku, JP;

Tetsuo Kiso, Chuo-ku, JP;

Inventors:

Takahiro Kuramochi, Chuo-ku, JP;

Norio Asai, Chuo-ku, JP;

Kazuhiro Ikegai, Chuo-ku, JP;

Seijiro Akamatsu, Chuo-ku, JP;

Hironori Harada, Chuo-ku, JP;

Noriko Ishikawa, Chuo-ku, JP;

Shohei Shirakami, Chuo-ku, JP;

Satoshi Miyamoto, Chuo-ku, JP;

Toshihiro Watanabe, Chuo-ku, JP;

Tetsuo Kiso, Chuo-ku, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/02 (2006.01); C07D 403/02 (2006.01); A61K 31/538 (2006.01); A61K 31/404 (2006.01);
U.S. Cl.
CPC ...
Abstract

There is provided a compound having a capsaicin receptor VR1 inhibitory activity and useful as a therapeutic agent for various pains including inflammatory pain and neurogenic pain, migraine, cluster headache, bladder diseases including overactive bladder, and the like. A benzamide derivative or a salt thereof wherein a benzene ring is attached to a D ring (a monocyclic or bicyclic hydrocarbon ring or a monocyclic or bicyclic heteroaromatic ring) through an amide bond, the benzene ring is directly bonded to an E ring (a monocyclic or bicyclic hydrocarbon ring or a monocyclic or bicyclic heteroaromatic ring), and the benzene ring is further bonded to A (an amino moiety, a monocyclic or bicyclic heterocycle) through L (a lower alkylene).


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